Rosiglitazone is a superior bronchodilator compared to chloroquine and β-adrenoceptor agonists in mouse lung slices.
Identifieur interne : 001006 ( Main/Exploration ); précédent : 001005; suivant : 001007Rosiglitazone is a superior bronchodilator compared to chloroquine and β-adrenoceptor agonists in mouse lung slices.
Auteurs : Chantal Donovan ; Mirjam Simoons ; James Esposito ; Jean Ni Cheong ; Meaghan Fitzpatrick ; Jane Elizabeth Bourke [Australie]Source :
- Respiratory research [ 1465-993X ] ; 2014.
Descripteurs français
- KwdFr :
- MESH :
- pharmacologie : Agonistes bêta-adrénergiques, Bronchodilatateurs, Chloroquine, Thiazolidinediones.
- physiologie : Poumon.
- Animaux, Mâle, Poumon, Souris, Souris de lignée BALB C, Techniques de culture d'organes.
English descriptors
- KwdEn :
- MESH :
- chemical , pharmacology : Adrenergic beta-Agonists, Bronchodilator Agents, Chloroquine, Thiazolidinediones.
- drug effects : Lung.
- physiology : Lung.
- Animals, Male, Mice, Mice, Inbred BALB C, Organ Culture Techniques, Rosiglitazone.
Abstract
Current therapy for relieving bronchoconstriction may be ineffective in severe asthma, particularly in the small airways. The aim of this study was to further characterise responses to the recently identified novel bronchodilators rosiglitazone (RGZ) and chloroquine (CQ) under conditions where β-adrenoceptor agonist efficacy was limited or impaired in mouse small airways within lung slices.
DOI: 10.1186/1465-9921-15-29
PubMed: 24621080
Affiliations:
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Le document en format XML
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The aim of this study was to further characterise responses to the recently identified novel bronchodilators rosiglitazone (RGZ) and chloroquine (CQ) under conditions where β-adrenoceptor agonist efficacy was limited or impaired in mouse small airways within lung slices.</div></front></TEI><affiliations><list><country><li>Australie</li></country><region><li>Victoria (État)</li></region><settlement><li>Melbourne</li></settlement><orgName><li>Université de Melbourne</li></orgName></list><tree><noCountry><name sortKey="Donovan, Chantal" sort="Donovan, Chantal" uniqKey="Donovan C" first="Chantal" last="Donovan">Chantal Donovan</name><name sortKey="Esposito, James" sort="Esposito, James" uniqKey="Esposito J" first="James" last="Esposito">James Esposito</name><name sortKey="Fitzpatrick, Meaghan" sort="Fitzpatrick, Meaghan" uniqKey="Fitzpatrick M" first="Meaghan" last="Fitzpatrick">Meaghan Fitzpatrick</name><name sortKey="Ni Cheong, Jean" sort="Ni Cheong, Jean" uniqKey="Ni Cheong J" first="Jean" last="Ni Cheong">Jean Ni Cheong</name><name sortKey="Simoons, Mirjam" sort="Simoons, Mirjam" uniqKey="Simoons M" first="Mirjam" last="Simoons">Mirjam Simoons</name></noCountry><country name="Australie"><region name="Victoria (État)"><name sortKey="Bourke, Jane Elizabeth" sort="Bourke, Jane Elizabeth" uniqKey="Bourke J" first="Jane Elizabeth" last="Bourke">Jane Elizabeth Bourke</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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